Many drug products for intravenous use are premixed in diluents. Called ready-to-use (RTU) products, they come packaged in flexible plastic containers or, in some cases, glass. Unless precluded by physicochemical factors—adsorption or reactivity, for example—flexible containers are preferred because they are safer in handling and storage. They are also durable and weigh less than glass containers.
This article on the history and impact of liquid chromatography in the pharmaceutical industry is the third in a new series for Pharmaceutical Formulation & Quality. In “PharmaTools: Technologies That Changed Pharma and Biotech,” we look at various technologies such as liquid chromatography that have played a key role and had an indelible impact on the pharma and biotech industries.
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An alternative method of producing Tamiflu (oseltamivir phosphate, Roche) may lower the cost of producing the drug and increase supplies worldwide, researchers in Singapore suggest. They described a method of synthesizing the drug’s active ingredient using a less expensive raw material than the one currently used.
A new edition of the U.S. Pharmacopeia-National Formulary (USP-NF) that was to become official in May has been recalled due to errors introduced during a redesign of the publication, according to the U.S. Pharmacopeial Convention (USP). The publication’s current edition, USP 32-NF 27, will remain in effect until the new version of the document, dubbed USP 33-NF 28 Reissue, is reissued and becomes official, the USP announced in January.
