It may sound farfetched, even futuristic, but the world of drug delivery is evolving and there are a few companies jockeying for position with innovations that include a nasal spray that thinks for you, a microchip that controls how much drug you take, and an eye medication without those cold drops.

During the lengthy transition from discovery to commercialization, new chemical and biopharmaceutical processes must be scaled up to operate in production-scale equipment. When it comes to process scale-up, the sooner the better.

How does a formulator assess palatability and select the best combination of sweeteners and flavors from the wide array available?

Quality Systems
Building in Real Time
By John P. Helfrich and Kenneth N. Rapp
Doing so can reduce review times by over 50 percent and minimize re-work and internal investigation processes yielding overall operational QA/QC cost improvements of over 25 percent

ISO
Laboratory Integrity
By Dr. George Rodrigues
New ISO Standard Answers Growing demand for Data Integrity in the Laboratory

Endotoxin Detection
Reckoning Recombiant Factor C
By Lin Chen
Sensitive endotoxin detection can be done with an assay based upon the recombinant factor C

TOC
Moisture Management
By Dr. M.Y.Z. AboulEish and Dr. R.H. Clifford
Control moisture in Total Organic Carbon Analyzers

PHARMA IT

LIMS
Off-the-Shelf LIMS
By Richard Wagner
Commercial Packages Close the Functionality Gap

Security
Information Lockdown
By Adam Bosnian
AstraZeneca Safeguards R&D Data with Cyber-Ark Vault Technology